Primate Gene Therapy
Diverse NHP species including Cynomolgus monkeys, Rhesus monkeys, African Green Monkeys, & Marmosets. Our Large colonies allow for rapid screening to obtain anti-AAV seronegative study candidates.
Screening capability for array of anti-AAV antibodies and neutralizing antibodies serotypes including AAV1, AAV2, AAV3, AAV4, AAV5, AAV6, AAV7, AAV8, AAV9, AAVrh10, AAVhu68.
Barrier housing allowing for maintaining pre-screened AAV negative primates to support programs through completion with no study delays due to high seropositive rates or unexpected seroconversion.
Large domestic breeding colonies allowing for NHP studies at any age range.
Genetic, small molecule and protein-based biomarkers.
Expert in multiple gene therapy delivery routes including:
- Intrahepatic
- Intrathecal
- Intraocular
- Intravenous
- Intratracheal
- Intramuscular
- Intranasal
- Intraperitoneal
- Intracerebroventricular
- Intravitreal
- Expert in repeated biopsies, surgical tissue excisions, and CSF sampling.
- Partial or full sterile tissue collection with gene and protein expression quantification or samples shipped to sponsor.
